Cloned (Comment) | Organism |
---|---|
expression in baculovirus-infected insect cells | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0034 | - |
cannabinol | isoform UGT1A9, pH 7.4, 37°C | Homo sapiens | |
0.0073 | - |
(+-)-11-hydroxy-DELTA9-tetrahydrocannabinol | isoform UGT1A9, pH 7.4, 37°C | Homo sapiens | |
0.019 | - |
cannabinol | isoform UGT1A7, pH 7.4, 37°C | Homo sapiens | |
0.044 | - |
cannabinol | isoform UGT1A8, pH 7.4, 37°C | Homo sapiens | |
0.059 | - |
cannabinol | isoform UGT1A10, pH 7.4, 37°C | Homo sapiens | |
0.068 | - |
(-)-11-nor-9-carboxy-DELTA9-tetrahydrocannabinol | isoform UGT1A3, pH 7.4, 37°C | Homo sapiens | |
0.072 | - |
(+-)-11-hydroxy-DELTA9-tetrahydrocannabinol | isoform UGT1A10, pH 7.4, 37°C | Homo sapiens | |
0.17 | - |
(-)-11-nor-9-carboxy-DELTA9-tetrahydrocannabinol | isoform UGT1A1, pH 7.4, 37°C | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(+-)-11-hydroxy-DELTA9-tetrahydrocannabinol + UDP-glucuronate | substrate for isoforms UGT1A9 and UGT1A10 | Homo sapiens | ? + UDP | - |
? | |
(-)-11-nor-9-carboxy-DELTA9-tetrahydrocannabinol + UDP-glucuronate | substrate for isoforms UGT1A1 and UGT1A3, no substrate for UGT1A9 and UGT1A10 | Homo sapiens | ? + UDP | - |
? | |
cannabinol + UDP-glucuronate | substrate for hepatic isoform UGT1A9 and extrahepatic UGT1A7, UGT1A8, and UGT1A10 | Homo sapiens | ? + UDP | - |
? |