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Literature summary for 2.4.1.17 extracted from
- Isoform-specific regulation of uridine diphosphate-glucuronosyltransferase 2B enzymes in the human prostate: differential consequences for androgen and bioactive lipid inactivation (2006), Endocrinology, 147, 5431-5442.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O75310 | - |
- |
| Homo sapiens | O75795 | - |
- |
| Homo sapiens | P06133 | - |
- |
| Homo sapiens | P16662 | - |
- |
| Homo sapiens | P36537 | - |
- |
| Homo sapiens | P54855 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| LNCaP cell | - |
Homo sapiens | - |
| LNCaP cell | low activity, UGT2B4 | Homo sapiens | - |
| LNCaP cell | low activity, UGT2B7 | Homo sapiens | - |
| LNCaP cell | UGT2B10 | Homo sapiens | - |
| LNCaP cell | UGT2B17 | Homo sapiens | - |
| additional information | no activity in prostate epithelial cells, UGT2B10 | Homo sapiens | - |
| additional information | no activity in prostate epithelial cells, UGT2B17 | Homo sapiens | - |
| additional information | no activity in prostate epithelial cells, UGT2B4 | Homo sapiens | - |
| additional information | no activity in prostate epithelial cells, UGT2B7 | Homo sapiens | - |
| prostate epithelium cell line | androgens do not only affect their own inactivation but also influence the levels of monohydroxy-fatty acids by regulating the expression of UGT2B enzymes in an isoform-specific manner | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 12-hydroxyeicosatetraenoic acid + UDP-glucuronate | - |
Homo sapiens | ? | - |
? |  |
| 13-hydroxyoctadecadienoic acid + UDP-glucuronate | - |
Homo sapiens | ? | - |
? | |
| 5alpha-androstane-3alpha,17beta-diol + UDP-glucuronate | - |
Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| UGT2B10 | - |
Homo sapiens |
| UGT2B11 | - |
Homo sapiens |
| UGT2B15 | - |
Homo sapiens |
| UGT2B17 | - |
Homo sapiens |
| UGT2B4 | - |
Homo sapiens |
| UGT2B7 | - |
Homo sapiens |
| uridine diphosphate-glucuronosyltransferase 2B10 | - |
Homo sapiens |
| uridine diphosphate-glucuronosyltransferase 2B11 | - |
Homo sapiens |
| uridine diphosphate-glucuronosyltransferase 2B15 | - |
Homo sapiens |
| uridine diphosphate-glucuronosyltransferase 2B17 | - |
Homo sapiens |
| uridine diphosphate-glucuronosyltransferase 2B4 | - |
Homo sapiens |
| uridine diphosphate-glucuronosyltransferase 2B7 | - |
Homo sapiens |
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