Activating Compound | Comment | Organism | Structure |
---|---|---|---|
alamethicin | - |
Homo sapiens | |
Brij58 | - |
Homo sapiens | |
additional information | sonication activates | Homo sapiens | |
phosphate | activity in phosphate buffer is higher than in Tris/malate buffer containing 5 mM sucrose | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics, at different conditions with different activators and different substrates, microsomes or recombinant isozymes, overview | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isozymes UGT1A1, UGT1A6, UGT1A9, UGT2B7, and UGT2B15 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
activity at different conditions with different activators and different substrates, microsomes or recombinant isozymes, overview | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | substrate specificities of different isozymes | Homo sapiens | ? | - |
? | |
UDP-glucuronate + 3,17-estradiol | isozyme UGT1A1 | Homo sapiens | UDP + 17-estradiol 3-O-glucuronide | - |
? | |
UDP-glucuronate + 3,17-estradiol | isozyme UGT1A1 | Homo sapiens | UDP + 3-estradiol 17-O-glucuronide | - |
? | |
UDP-glucuronate + androstane-3,17-diol | isozyme UGT2B15 | Homo sapiens | UDP + androstane-3,17-diol 17-O-beta-D-glucuronide | - |
? | |
UDP-glucuronate + anthraflavic acid | isozyme UGT1A1 | Homo sapiens | UDP + anthraflavic acid 2-glucuronide | - |
? | |
UDP-glucuronate + buprenorphine | isozyme UGT1A1 | Homo sapiens | UDP + buprenorphine glucuronide | - |
? | |
UDP-glucuronate + ethinylestradiol | isozyme UGT1A1 | Homo sapiens | UDP + ethinylestradiol glucuronide | - |
? | |
UDP-glucuronate + morphine | isozyme UGT1A1 | Homo sapiens | UDP + morphine-3-beta-D-glucuronide | - |
? | |
UDP-glucuronate + morphine | isozyme UGT1A1 | Homo sapiens | UDP + morphine-6-beta-D-glucuronide | - |
? | |
UDP-glucuronate + naphthol | isozyme UGT1A6 | Homo sapiens | UDP + naphthol glucuronide | - |
? | |
UDP-glucuronate + propofol | isozyme UGT1A9 | Homo sapiens | UDP + propofol beta-D-glucuronide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UDP-glucuronosyltransferase | - |
Homo sapiens |
UGT | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.1 | 7.4 | assay at | Homo sapiens |