Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Phospholipids | no effect on glucuronidation of 1-naphthol, 4-nitrophenol, testosterone, 4-methylumbelliferone, morphine | Mus musculus | |
Phospholipids | 2fold activation of glucuronidation of 3-hydroxybenzo[a]pyrene, between 3fold and 4fold activation of glucuronidation of phenolphthalein | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | immunochemical experiments | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Mus musculus | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
51000 | - |
x * 51000 | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phospholipoprotein | less than 1 mol phospholipid per mol of enzyme | Mus musculus |
Purification (Comment) | Organism |
---|---|
- |
Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
Storage Stability | Organism |
---|---|
4°C, at least 6 days | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-naphthol + UDP-glucuronate | - |
Mus musculus | naphth-1-yl-beta-D-glucuronide + UDP | - |
? | |
3-hydroxybenzo[a]pyrene + UDPglucuronate | - |
Mus musculus | UDP + 3-hydroxybenzo[a]pyrene-O-glucuronide | - |
? | |
4-methylumbelliferone + UDP-glucuronate | - |
Mus musculus | UDP + 4-methylumbelliferyl-7-O-beta-D-glucuronide | - |
? | |
4-nitrophenol + UDP-glucuronate | - |
Mus musculus | 4-nitrophenyl beta-D-glucuronide + UDP | - |
? | |
morphine + UDP-glucuronate | - |
Mus musculus | UDP + morphine 3,6-diglucuronide | - |
? | |
phenolphthalein + UDPglucuronate | - |
Mus musculus | UDP + phenolphthalein O-glucuronide | - |
? | |
testosterone + UDPglucuronate | - |
Mus musculus | UDP + testosterone O-glucuronide | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | all values determined by SDS-PAGE | Mus musculus |
? | x * 51000 | Mus musculus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
24 | - |
1 d, more than 50% loss of activity | Mus musculus |