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Literature summary for 2.4.1.165 extracted from

  • Montiel, M.D.; Krzewinski-Recchi, M.A.; Delannoy, P.; Harduin-Lepers, A.
    Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain (2003), Biochem. J., 373, 369-379.
    View publication on PubMedView publication on EuropePMC
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KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.11
-
 UDP-N-acetyl-D-galactosamine pH 6.2, 37°C Homo sapiens
0.38
-
 Neu5Ac-alpha(2-3)Gal-beta(1-3)GlcNAc-beta-1-O-benzyl pH 6.2, 37°C Homo sapiens
0.94
-
 fetuin pH 6.2, 37°C Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens involved in formation of blood group Sda/CAD antigen ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q8NHY0 short transkript; expression in COS-7 cells
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information detected in various amounts in all cell types studied Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information involved in formation of blood group Sda/CAD antigen Homo sapiens ?
-
 ?
additional information analysis of acceptor substrate specificity, no substrate: ganglioside GM3, 3’-sulfolactose, 3’-O-methylcarboxyllactose Homo sapiens ?
-
 ?
UDP-N-acetyl-D-galactosamine + alpha(2-3)-sialylated glycoprotein
-
 Homo sapiens UDP + GalNAc-beta(1-4)(Neu5Ac(2-3))Gal-beta-1-protein
-
 ?
UDP-N-acetyl-D-galactosamine + fetuin
-
 Homo sapiens UDP + ?
-
 ?
UDP-N-acetyl-D-galactosamine + Neu5Ac-alpha(2-3)Gal-beta(1-3)GlcNAc-beta-1-O-benzyl
-
 Homo sapiens UDP + ?
-
 ?