Any feedback?
Literature summary for 2.4.1.16 extracted from
- Properties of chitin synthetase in isolated chitosomes from yeast cells of Mucor rouxii (1977), J. Biol. Chem., 252, 3338-3343.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| GlcNAc | stimulates | Amylomyces rouxii |  |
General Stability
| General Stability | Organism |
|---|---|
| the zymogen is highly stable | Amylomyces rouxii |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ADP | 6.25 mM | Amylomyces rouxii | |
| AMP | 6.25 mM | Amylomyces rouxii | |
| ATP | 6.25 mM | Amylomyces rouxii | |
| Ca2+ | 5-10 mM | Amylomyces rouxii | |
| Co2+ | 5-10 mM | Amylomyces rouxii | |
| Polyoxin D | - |
Amylomyces rouxii | |
| UDP | - |
Amylomyces rouxii | |
| UMP | 6.25 mM | Amylomyces rouxii | |
| UTP | 6.25 mM | Amylomyces rouxii | |
| Zn2+ | 5-10 mM | Amylomyces rouxii | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| chitosome | - |
Amylomyces rouxii | 45009 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Co2+ | optimal concentration is 5-20 mM | Amylomyces rouxii | |
| Mg2+ | Mg2+ or Mn2+ required | Amylomyces rouxii | |
| Mn2+ | Mn2+ or Mg2+ required | Amylomyces rouxii | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 700000 | - |
gel filtration | Amylomyces rouxii |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Amylomyces rouxii | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| proteolytic modification | enzyme exists in the zymogenic form and requires proteolytic activation | Amylomyces rouxii |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Amylomyces rouxii |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.01639 | - |
- |
Amylomyces rouxii |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n | - |
Amylomyces rouxii | UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1 | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 40 | 50 | 5 min, 20-25% loss of activity | Amylomyces rouxii |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | - |
- |
Amylomyces rouxii |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00065 | - |
polyoxin | - |
Amylomyces rouxii | |
| 0.4 | - |
UDP | - |
Amylomyces rouxii | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2026.1 (March 2026)
Legal
Curated at
Member of
![DSMZ Digital Diversity]()
![Global Core Biodata Resource]()
![ELIXIR Core Data Resource]()
![German Network for Bioinformatics Infrastructure]()
