Literature summary for 2.4.1.16 extracted from

Rast, D.M.; Bartnicki-Garcia, S.
Effects of amphotericin B, nystatin, and other polyene antibiotics on chitin synthase (1981), Proc. Natl. Acad. Sci. USA, 78, 1233-1236.

Search for more literature for 2.4.1.16

Activating Compound

Activating Compound	Comment	Organism	Structure
Nystatin	0.05 mM, marked stimulation	Amylomyces rouxii

Inhibitors

Inhibitors	Comment	Organism	Structure
amphotericin	noncompetitive	Amylomyces rouxii
Filipin	weak	Amylomyces rouxii
Nystatin	-	Amylomyces rouxii

Organism

Organism	UniProt	Comment	Textmining
Amylomyces rouxii	-	-	-
Amylomyces rouxii IM-80 / CCUG 22422 / CBS 416.77 / CCM F-220 / DSM 1191 / ATCC 24905	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n	-	Amylomyces rouxii	UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1	-	?
UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n	-	Amylomyces rouxii IM-80 / CCUG 22422 / CBS 416.77 / CCM F-220 / DSM 1191 / ATCC 24905	UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.13	-	Amphotericin B	-	Amylomyces rouxii

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Release 2026.1 (March 2026)