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Literature summary for 2.4.1.16 extracted from
- Chitin synthase activity from the slime variant of Neurospora crassa (1979), Biochim. Biophys. Acta, 571, 224-232.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| phosphatidylethanolamine | stimulates | Neurospora crassa |  |
| phosphatidylinositol | stimulates | Neurospora crassa | |
| phosphatidylserine | stimulates | Neurospora crassa | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| UDP | competitive with respect to UDP-GlcNAc | Neurospora crassa | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | maximal activity in presence of 1 mM MgCl2 | Neurospora crassa | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Neurospora crassa | - |
wall-less variant | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n | - |
Neurospora crassa | UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1 | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | 8.2 | - |
Neurospora crassa |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 2.2 | - |
UDP | - |
Neurospora crassa | |
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