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Literature summary for 2.4.1.16 extracted from

  • Causier, B.E.; Milling, R.J.; Foster, S.G.; Adams, D.J.
    Characterization of chitin synthase from Botrytis cinerea (1994), Microbiology, 140, 2199-2205.
No PubMed abstract available
Search for more literature for 2.4.1.16

Activating Compound

Activating Compound Comment Organism Structure
GlcNAc stimulates Botrytis cinerea

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Botrytis cinerea

Inhibitors

Inhibitors Comment Organism Structure
edifenphos non-competitive Botrytis cinerea
nikkomycin Z
-
 Botrytis cinerea
Polyoxin D
-
 Botrytis cinerea
UDP
-
 Botrytis cinerea

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2
-
 UDP-GlcNAc
-
 Botrytis cinerea

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ dependent upon presence of divalent cation, Mn2+ is most effective Botrytis cinerea

Organism

Organism UniProt Comment Textmining
Botrytis cinerea
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification preincubation with trypsin results in approximately 4fold increase in activity Botrytis cinerea

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n
-
 Botrytis cinerea UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
35
-
-
 Botrytis cinerea

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0001
-
 nikkomycin Z
-
 Botrytis cinerea
0.006
-
 Polyoxin D
-
 Botrytis cinerea
0.054
-
 edifenphos
-
 Botrytis cinerea
0.19
-
 UDP
-
 Botrytis cinerea