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Literature summary for 2.4.1.155 extracted from

  • Kim, Y.S.; Ahn, Y.H.; Song, K.J.; Kang, J.G.; Lee, J.H.; Jeon, S.K.; Kim, H.C.; Yoo, J.S.; Ko, J.H.
    Overexpression and beta-1,6-N-acetylglucosaminylation-initiated aberrant glycosylation of TIMP-1: a double whammy strategy in colon cancer progression (2012), J. Biol. Chem., 287, 32467-32478.
    View publication on PubMedView publication on EuropePMC
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Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus
-
 Homo sapiens 5794
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colonic adenocarcinoma cell
-
 Homo sapiens
-
WiDr cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
GnT-V
-
 Homo sapiens
Mgat5
-
 Homo sapiens
N-acetylglucosaminyltransferase-V
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function concomitant overexpression of tissue inhibitor of metalloproteinase-1 and N-acetylglucosaminyltransferase V directs accelerated tumor growth and cancer progression in vivo and in vitro. Cells with high enzyme expression show higher collagenolytic activity, compared with the mock cells. Membrane type-1-matrix metalloproteinase expression is induced by N-acetylglucosaminyltransferase V overexpression Homo sapiens