Literature summary for 2.4.1.155 extracted from

Guo, P.; Wang, Q.Y.; Guo, H.B.; Shen, Z.H.; Chen, H.L.
N-acetylglucosaminyltransferase V modifies the signaling pathway of epidermal growth factor receptor (2004), Cell. Mol. Life Sci., 61, 1795-1804.

Search for more literature for 2.4.1.155

Application

Application	Comment	Organism
biotechnology	transfection of sense cDNA of enzyme results in increase in the N-acetylglucosamine-beta1,6-mannose-alpha1,3-branch of epidermal growth factor receptor. Transfection with antisense CDNA of enzyme rsults in reverse reaction. Altered expression of enzyme will change the glycan structure and function of epidermal growth factor receptor, which may modify downstream signal transduction	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
UDP-N-acetyl-D-glucosamine + epidermal growth factor receptor	Homo sapiens	-	UDP + N-acetylglucosamine-beta-1,6-mannose-alpha-1,3-branch of epidermal growth factor receptor	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	expression in human H7721 hepatocarcinoma cells	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-N-acetyl-D-glucosamine + epidermal growth factor receptor	-	Homo sapiens	UDP + N-acetylglucosamine-beta-1,6-mannose-alpha-1,3-branch of epidermal growth factor receptor	-	?

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Release 2023.1 (January 2023)