BRENDA - Enzyme Database
show all sequences of 2.4.1.153

Lipid-mediated glycosylation in human liver. Characterization of the enzymatic transfer of N-acetylglucosamine from UDP-N-acetylglucosamine and mannose from GDP-mannose to dolichyl phosphate

Alhadeff, J.A.; Watkins P.; Enzyme 31, 90-103 (1984)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
detergent
required at low concentrations
Homo sapiens
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
particle-bound
90% of the activity is particulate
Homo sapiens
-
-
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
divalent cation
required
Homo sapiens
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Homo sapiens
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
liver
-
Homo sapiens
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
UDP-N-acetyl-D-glucosamine + dolichyl phosphate
-
488620
Homo sapiens
UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate
-
-
-
?
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.8
-
broad with maximum near pH 7.8
Homo sapiens
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
detergent
required at low concentrations
Homo sapiens
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
particle-bound
90% of the activity is particulate
Homo sapiens
-
-
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
divalent cation
required
Homo sapiens
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
liver
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
UDP-N-acetyl-D-glucosamine + dolichyl phosphate
-
488620
Homo sapiens
UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate
-
-
-
?
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.8
-
broad with maximum near pH 7.8
Homo sapiens
Other publictions for EC 2.4.1.153
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
732558
Larkin
Biochemical evidence for an al ...
Methanococcus voltae, Methanococcus voltae PS
Nat. Chem. Biol.
9
367-373
2013
-
-
1
-
-
-
1
-
2
3
1
2
-
2
-
-
1
-
-
-
-
-
4
1
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
2
3
1
2
-
-
-
1
-
-
-
-
4
1
1
-
-
-
1
-
-
-
-
1
1
-
-
-
660115
Koizumi
-
A chimeric tunicamycin resista ...
Arabidopsis thaliana
Plant Biotechnol.
20
305-309
2003
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
488620
Alhadeff
Lipid-mediated glycosylation i ...
Homo sapiens
Enzyme
31
90-103
1984
1
-
-
-
-
-
-
-
1
1
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
488621
Alhadeff
Dolichyl phosphate-mannosyltra ...
Homo sapiens
Clin. Chim. Acta
134
1-9
1983
2
-
-
-
-
-
-
-
-
1
-
1
-
1
-
-
-
-
-
1
1
-
2
-
-
-
-
-
1
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
1
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-