Literature summary for 2.4.1.152 extracted from

M�nster, J.; Ziegelm�ller, P.; Spillner, E.; Bredehorst, R.
High level expression of monomeric and dimeric human alpha1,3-fucosyltransferase V (2006), J. Biotechnol., 121, 448-457.

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Cloned(Commentary)

Cloned (Comment)	Organism
truncated constructs lacking the transmembrane region and the cytosolic N-terminus, are expressed in baculovirus-infected Trichoplusia ni insect cells and in two non-lytic expression systems, stably transfect human HEK 293 and Trichoplusia ni cells. Since secretion of some glycosyltransferases is controlled by formation of dimeric molecules via disulfide bonds, one of the fucosyltransferase V constructs contains the N-terminal cysteine residue 64 for dimerization, whereas this residue is replaced in the other construct by serine	Homo sapiens

Cloned (Comment)

Organism

truncated constructs lacking the transmembrane region and the cytosolic N-terminus, are expressed in baculovirus-infected Trichoplusia ni insect cells and in two non-lytic expression systems, stably transfect human HEK 293 and Trichoplusia ni cells. Since secretion of some glycosyltransferases is controlled by formation of dimeric molecules via disulfide bonds, one of the fucosyltransferase V constructs contains the N-terminal cysteine residue 64 for dimerization, whereas this residue is replaced in the other construct by serine

Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
C64S	FucT V mutant is secreted exclusively as monomer	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens

Synonyms

Synonyms	Comment	Organism
alpha1,3-fucosyltransferase V	-	Homo sapiens
fucosyltransferase V	-	Homo sapiens
FucT V	-	Homo sapiens

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Release 2023.1 (January 2023)