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Literature summary for 2.4.1.152 extracted from

  • Satoh, T.; Kanai, Y.; Wu, M.; Yokozeki, H.; Kannagi, R.; Lowe, J.B.; Nishioka, K.
    Synthesis of alpha(1,3) fucosyltransferases IV- and VII-dependent eosinophil selectin ligand and recruitment to the skin (2005), Am. J. Pathol., 167, 787-796.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.152

Application

Application Comment Organism
medicine FT-IV and FT-VII are both important contributors to selectin-dependent eosinophil recruitment to the skin and may represent therapeutic targets in which eosinophil recruitment contributes to pathophysiology Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information double knock-out mice deficient for both FT-IV and FT-VII show an essential absence of eosinophil recruitment to the dermis Mus musculus
additional information FT-IV deficient mice show a significant decrease in eosinophil recruitment to the skin Mus musculus
additional information FT-VII deficient mice show a decrease in eosinophil recruitment to the skin Mus musculus

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Mus musculus Q11127
-
-
Mus musculus Q11131
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-

Source Tissue

Source Tissue Comment Organism Textmining
eosinophil FT-IV mRNA is the predominant transcript in eosinophils isolated from human blood, TGF-beta1 upregulates FT-IV mRNA expression Homo sapiens
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eosinophil FT-VII mRNA is weakly expressed in eosinophils isolated from human blood, its expression is up-regulated by TGF-beta1 to some extent Homo sapiens
-

Synonyms

Synonyms Comment Organism
alpha(1,3)fucosyltransferase IV
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 Homo sapiens
alpha(1,3)fucosyltransferase IV
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 Mus musculus
alpha(1,3)fucosyltransferase VII
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 Homo sapiens
alpha(1,3)fucosyltransferase VII
-
 Mus musculus
FT-IV
-
 Homo sapiens
FT-IV
-
 Mus musculus
FT-VII
-
 Homo sapiens
FT-VII
-
 Mus musculus