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Literature summary for 2.4.1.152 extracted from

  • Johnson, P.H.; Watkins, W.M.
    Sialyl compounds as acceptor substrates for human alpha-3- and alpha-3/4-L-fucosyltransferases (1985), Biochem. Soc. Trans., 13, 1119-1120.
No PubMed abstract available
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KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.2
-
 NeuAcalpha(2,3)Galbeta(1,4)GlcNAc
-
 Homo sapiens
0.7
-
 Fucalpha(1,2)Galbeta(1,4)GlcNAc
-
 Homo sapiens
1.4
-
 Galbeta(1,4)GlcNAc
-
 Homo sapiens
3.9
-
 NeuAcalpha(2,3)Galbeta(1,4)Glc
-
 Homo sapiens
6.7
-
 Fucalpha(1,2)Galbeta(1,4)Glc
-
 Homo sapiens
25
-
 Galbeta(1,4)Glc
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-beta-L-fucose + NeuAcalpha(2,3)Galbeta(1,4)Glc
-
 Homo sapiens ?
-
 ?
GDP-L-fucose + Fucalpha(1,2)Galbeta(1,4)Glc i.e. 2'-fucosyllactose, 17% of the activity with Galbeta(1,4)GlcNAc Homo sapiens GDP + Fucalpha(1,2)Galbeta(1,4)(Fucalpha(1,3))Glc
-
 ?
GDP-L-fucose + Fucalpha(1,2)Galbeta(1,4)GlcNAc 162% of the activity with Galbeta(1,4)GlcNAc Homo sapiens GDP + Fucalpha(1,2)Galbeta(1,4)(Fucalpha(1,3))GlcNAc
-
 ?
GDP-L-fucose + Galbeta(1,4)-Glc 3% of the activity with Galbeta(1,4)GlcNAc Homo sapiens GDP + Galbeta(1,4)(Fucalpha(1,3))Glc
-
 ?
GDP-L-fucose + Galbeta(1,4)GlcNAc i.e. N-acetyllactosamine Homo sapiens GDP + Galbeta(1,4)(Fucalpha(1,3))GlcNAc
-
 ?
GDP-L-fucose + NeuAcalpha(2,3)Galbeta(1,4)GlcNAc 147% of the activity with Galbeta(1,4)GlcNAc Homo sapiens GDP + NeuAcalpha(2,3)Galbeta(1,4)(Fucalpha(1,3))GlcNAc
-
 ?
additional information no activity with Galbeta(1,3)GlcNAc, NeuAcalpha2,6Galbeta(1,4)GlcNAc, NeuAcalpha2,8NeuAc and NeuAcalpha2,6Galbeta(1,4)Glc Homo sapiens ?
-
 ?