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Literature summary for 2.4.1.150 extracted from

  • Chen, G.Y.; Kurosawa, N.; Muramatsu, T.
    Functional analysis of promoter activity of murine beta-1,6-N-acetylglucosaminyltransferase (2001), Gene, 275, 253-259.
    View publication on PubMed
Search for more literature for 2.4.1.150

Cloned(Commentary)

Cloned (Comment) Organism
2 isoforms IGnT A and IGnT B are produced by alternative splicing of the IGnT gene, the C-terminal 1/4 of IGnT B is identical to that of IGnT A Mus musculus
expression of each isoform is controlled by a different promoter, characterization of the promoters: GT boxes play crucial roles in transcriptional regulation of the genes Mus musculus
IGnT A is cloned Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information mutation experiments at the GT boxes of the promoters of IGnT A and B genes Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-N-acetyl-D-glucosamine + poly-N-acetyllactosamine Mus musculus forms branches in poly-N-acetyllactosamines, which bear the I blood group antigen ?
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
F9 cell F9 embryonal carcinoma cells moderately express IGnT A and B Mus musculus
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intestine strong expression of IGnT A and B in adults Mus musculus
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kidney strong expression of IGnT A and B in adults Mus musculus
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liver strong expression of IGnT A and B in adults Mus musculus
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mammary gland moderate expression of IGnT A and B Mus musculus
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additional information no expression of IGnT A and B in N2a cells Mus musculus
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submaxillary gland moderate expression of IGnT A and B Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information 2 isoforms IGnT A and IGnT B, C-terminal 1/4 of IGnT B is identical to that of IGnT A, the rest of the sequences shows 63% identity Mus musculus ?
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 ?
UDP-N-acetyl-D-glucosamine + poly-N-acetyllactosamine forms branches in poly-N-acetyllactosamines Mus musculus ?
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 ?
UDP-N-acetyl-D-glucosamine + poly-N-acetyllactosamine forms branches in poly-N-acetyllactosamines, which bear the I blood group antigen Mus musculus ?
-
 ?