Cloned (Comment) | Organism |
---|---|
gene B3GNT3, recombinant expression in CHO-K1 cells. Glycosylation-related genes in CHO-K1 cells are present, but strictly suppressed and regulated. CHO cells are transiently co-transfected with plasmids encoding extended C1 beta3GnT3, C2 beta6GnT1, or C3 beta3GnT6 with or without ST6Gal I or CHST4, respectively, and resulting O-glycan and core chain spectrum, overview | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y2A9 | gene B3GNT3 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colorectal adenocarcinoma cell | - |
Homo sapiens | - |
HT-29 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
beta1,3-N-acetylglucosaminyltransferase 3 | - |
Homo sapiens |
core 1 extension enzyme | - |
Homo sapiens |
extended C1 beta3GnT3 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
metabolism | O-glycan biosynthesis pathways and proposed O-glycan structures of selected glycosyltransferases, overview. Core 1 dominates the O-glycan repertoire. Core 1 can be further elongated by extended C1 beta3GnT3 enzyme to form extended core 1 structure, or be modified by C2 beta6GnT1 enzyme, EC 2.4.1.102, to form core 2 O-glycans. Regulation of O-glycan biosynthesis, overview. The extended C1 beta3GnT3 is competing withthe endogenous ST3Gal | Homo sapiens |