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Literature summary for 2.4.1.122 extracted from

  • Ju, T.; Brewer, K.; D'Souza, A.; Cummings, R.D.; Canfield, W.M.
    Cloning and expression of human core 1 beta1,3-galactosyltransferase (2002), J. Biol. Chem., 277, 178-186.
    View publication on PubMed
Search for more literature for 2.4.1.122

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination Mus musculus
DNA and amino acid sequence determination Rattus norvegicus
DNA and amino acid sequence determination Caenorhabditis elegans
DNA and amino acid sequence determination and analysis, transient functional expression in human 293T cells as wild-type and soluble, i.e. secreted into the medium, epitope-tagged protein, stable functional expression of the soluble epitope-tagged enzyme in CHO-K1 and Lec1-CHO cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information type II transmembrane protein Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Caenorhabditis elegans Q18515
-
-
Homo sapiens Q9NS00
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-
Mus musculus Q9JJ06
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Rattus norvegicus Q9JJ05
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-

Purification (Commentary)

Purification (Comment) Organism
partial, recombinant soluble epitope-tagged enzyme from 293T cell medium Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
colon low content Homo sapiens
-
heart high content Homo sapiens
-
kidney high content Homo sapiens
-
leukocyte
-
 Homo sapiens
-
liver high content Homo sapiens
-
lung
-
 Homo sapiens
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placenta high content Homo sapiens
-
skeletal muscle
-
 Homo sapiens
-
small intestine low content Homo sapiens
-
spleen low content Homo sapiens
-
thymus low content Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-galactose + glycoprotein N-acetyl-D-galactosamine threonine alpha-D-galactosamine is preferred to serine alpha-D-galactosamine Homo sapiens UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?
UDP-galactose + glycoprotein N-acetyl-D-galactosamine high specificity for N-acetylgalactosaminyl residues linked to serine or threonine Homo sapiens UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?
UDP-galactose + N-acetyl-alpha-D-galactosaminyl-phenyl
-
 Homo sapiens UDP + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-phenyl
-
 ?