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Literature summary for 2.4.1.109 extracted from
- Protein-O-mannosyltransferases in virulence and development (2008), Cell. Mol. Life Sci., 65, 528-544.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Mycobacterium tuberculosis | O-mannosylation of specific secretory proteins of the bacterial pathogen Mycobacterium tuberculosis contributes significantly to virulence | ? | - |
? |  |
| additional information | Candida albicans | O-mannosylation of specific secretory proteins of the human fungal pathogen Candida albicans contributes significantly to virulence | ? | - |
? | |
| additional information | Candida albicans | O-mannosylation of specific secretory proteins of the human fungal pathogen Candida albicans contributes significantly to virulence. PMT2 is essential for growth. Loss of a single PMT2 allele already sufficed to significantly retarded growth | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Candida albicans | O74189 | - |
- |
| Candida albicans | Q59X23 | - |
- |
| Candida albicans | Q5ACU3 | - |
- |
| Candida albicans | Q5ADM9 | - |
- |
| Candida albicans | Q9UVB5 | - |
- |
| Cryptococcus neoformans | - |
- |
- |
| Mycobacterium tuberculosis | - |
- |
- |
| Saccharomyces cerevisiae | P31382 | - |
- |
| Saccharomyces cerevisiae | P33775 | - |
- |
| Saccharomyces cerevisiae | P42934 | - |
- |
| Saccharomyces cerevisiae | P46971 | - |
- |
| Saccharomyces cerevisiae | P47190 | - |
- |
| Saccharomyces cerevisiae | P52867 | - |
- |
| Saccharomyces cerevisiae | Q06644 | - |
- |
| Schizosaccharomyces pombe | O13898 | - |
- |
| Schizosaccharomyces pombe | O42933 | - |
- |
| Schizosaccharomyces pombe | Q9C100 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | O-mannosylation of specific secretory proteins of the bacterial pathogen Mycobacterium tuberculosis contributes significantly to virulence | Mycobacterium tuberculosis | ? | - |
? | |
| additional information | O-mannosylation of specific secretory proteins of the human fungal pathogen Candida albicans contributes significantly to virulence | Candida albicans | ? | - |
? | |
| additional information | O-mannosylation of specific secretory proteins of the human fungal pathogen Candida albicans contributes significantly to virulence. PMT2 is essential for growth. Loss of a single PMT2 allele already sufficed to significantly retarded growth | Candida albicans | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Oma1 | - |
Schizosaccharomyces pombe |
| Oma2 | - |
Schizosaccharomyces pombe |
| Oma4 | - |
Schizosaccharomyces pombe |
| Omg1 | - |
Schizosaccharomyces pombe |
| Omg2 | - |
Schizosaccharomyces pombe |
| Omg4 | - |
Schizosaccharomyces pombe |
| PMT | - |
Mycobacterium tuberculosis |
| PMT1 | - |
Saccharomyces cerevisiae |
| PMT1 | - |
Candida albicans |
| PMT2 | - |
Saccharomyces cerevisiae |
| PMT2 | - |
Candida albicans |
| PMT3 | - |
Saccharomyces cerevisiae |
| PMT4 | - |
Saccharomyces cerevisiae |
| PMT4 | - |
Candida albicans |
| PMT5 | - |
Saccharomyces cerevisiae |
| PMT5 | - |
Candida albicans |
| Pmt6 | - |
Saccharomyces cerevisiae |
| Pmt6 | - |
Candida albicans |
| PMT7 | - |
Saccharomyces cerevisiae |
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