Activating Compound | Comment | Organism | Structure |
---|---|---|---|
phosphatidylcholine | stimulates | Candida albicans |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | above 5 mM | Candida albicans | |
phosphatidylinositol | - |
Candida albicans |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.075 | - |
biotin-Tyr-Thr-Ala-Val-NH2 | - |
Candida albicans | |
0.1 | - |
biotin-Tyr-Leu-Ala-Val-NH2 | - |
Candida albicans | |
0.25 | - |
Ac-Tyr-Ala-Thr-Ala-Val-NH2 | - |
Candida albicans | |
0.85 | - |
biotin-Tyr-Pro-Thr-Ala-Val-NH2 | - |
Candida albicans | |
2.2 | - |
Tyr-Ala-Thr-Ala-Val | - |
Candida albicans | |
2.5 | - |
Tyr-Leu-Thr-Ala-Val | - |
Candida albicans | |
4.3 | - |
Ac-Tyr-Asn-Pro-Thr-Ser-Val-NH2 | - |
Candida albicans | |
6.7 | - |
Ac-Ala-Thr-Ala-NH2 | - |
Candida albicans | |
7.3 | - |
Tyr-Pro-Thr-Ala-Val | - |
Candida albicans |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Candida albicans | 16020 | - |
microsome | - |
Candida albicans | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | not required | Candida albicans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dolichyl phosphate D-mannose + protein | Candida albicans | production of cell-wall mannoproteins | dolichyl phosphate + O-D-mannosylprotein | - |
? | |
dolichyl phosphate D-mannose + protein | Candida albicans 2005 E | production of cell-wall mannoproteins | dolichyl phosphate + O-D-mannosylprotein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida albicans | - |
2005 E | - |
Candida albicans 2005 E | - |
2005 E | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0000012 | - |
substrate YNPTSV | Candida albicans |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dolichyl beta-D-mannosyl phosphate + biotin-Tyr-Leu-Ala-Val-NH2 | - |
Candida albicans | ? | - |
? | |
dolichyl phosphate D-mannose + Ac-Ala-Thr-Ala-NH2 | - |
Candida albicans | dolichyl phosphate + O-D-mannosyl-Ac-Ala-Thr-Ala-NH2 | - |
? | |
dolichyl phosphate D-mannose + Ac-Tyr-Ala-Thr-Ala-Val-NH2 | - |
Candida albicans | dolichyl phosphate + O-D-mannosyl-Ac-Tyr-Ala-Thr-Ala-Val-NH2 | - |
? | |
dolichyl phosphate D-mannose + Ac-Tyr-Asn-Pro-Thr-Ser-Val-NH2 | - |
Candida albicans | dolichyl phosphate + O-D-mannosyl-Ac-Tyr-Asn-Pro-Thr-Ser-Val-NH2 | - |
? | |
dolichyl phosphate D-mannose + Ac-Tyr-Asn-Pro-Thr-Ser-Val-NH2 | - |
Candida albicans 2005 E | dolichyl phosphate + O-D-mannosyl-Ac-Tyr-Asn-Pro-Thr-Ser-Val-NH2 | - |
? | |
dolichyl phosphate D-mannose + biotin-Tyr-Ala-Thr-Ala-Val-NH2 | - |
Candida albicans | dolichyl phosphate + O-D-mannosyl-N-biotinyl-Tyr-Ala-Thr-Ala-Val-NH2 | - |
? | |
dolichyl phosphate D-mannose + biotin-Tyr-Pro-Thr-Ala-Val-NH2 | - |
Candida albicans | dolichyl phosphate + O-D-mannosyl-N-biotinyl-Tyr-Pro-Thr-Ala-Val-NH2 | - |
? | |
dolichyl phosphate D-mannose + biotin-Tyr-Thr-Ala-Val-NH2 | - |
Candida albicans | dolichyl phosphate + O-D-mannosyl-N-biotinyl-Tyr-Thr-Ala-Val-NH2 | - |
? | |
dolichyl phosphate D-mannose + protein | - |
Candida albicans | dolichyl phosphate + O-D-mannosylprotein | - |
? | |
dolichyl phosphate D-mannose + protein | the enzyme transfers mannosyl residues to the hydroxyl of serine or threonine residues | Candida albicans | dolichyl phosphate + O-D-mannosylprotein | - |
? | |
dolichyl phosphate D-mannose + protein | production of cell-wall mannoproteins | Candida albicans | dolichyl phosphate + O-D-mannosylprotein | - |
? | |
dolichyl phosphate D-mannose + protein | - |
Candida albicans 2005 E | dolichyl phosphate + O-D-mannosylprotein | - |
? | |
dolichyl phosphate D-mannose + protein | the enzyme transfers mannosyl residues to the hydroxyl of serine or threonine residues | Candida albicans 2005 E | dolichyl phosphate + O-D-mannosylprotein | - |
? | |
dolichyl phosphate D-mannose + protein | production of cell-wall mannoproteins | Candida albicans 2005 E | dolichyl phosphate + O-D-mannosylprotein | - |
? | |
dolichyl phosphate D-mannose + Tyr-Ala-Thr-Ala-Val | - |
Candida albicans | dolichyl phosphate + O-D-mannosyl-Tyr-Ala-Thr-Ala-Val | - |
? | |
dolichyl phosphate D-mannose + Tyr-Asn-Pro-Thr-Ser-Val | - |
Candida albicans | dolichyl phosphate + O-D-mannosyl-Tyr-Asn-Pro-Thr-Ser-Val | - |
? | |
dolichyl phosphate D-mannose + Tyr-Asn-Pro-Thr-Ser-Val | - |
Candida albicans 2005 E | dolichyl phosphate + O-D-mannosyl-Tyr-Asn-Pro-Thr-Ser-Val | - |
? | |
dolichyl phosphate D-mannose + Tyr-Leu-Thr-Ala-Val | - |
Candida albicans | dolichyl phosphate + O-D-mannosyl-Tyr-Leu-Thr-Ala-Val | - |
? | |
dolichyl phosphate D-mannose + Tyr-Pro-Thr-Ala-Val | - |
Candida albicans | dolichyl phosphate + O-D-mannosyl-Tyr-Pro-Thr-Ala-Val | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Candida albicans |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | 8 | the best buffers are bicine pH 7.7, tricine pH 8.0 and HEPES pH 7.5 | Candida albicans |