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Literature summary for 2.3.3.8 extracted from

  • Rodriguez, S.; Denby, C.M.; Van Vu, T.; Baidoo, E.E.; Wang, G.; Keasling, J.D.
    ATP citrate lyase mediates cytosolic acetyl-CoA biosynthesis increases mevalonate production in Saccharomyces cerevisiae (2016), Microb. Cell Fact., 15, 48.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.3.8

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae Mus musculus
expressed in Saccharomyces cerevisiae Aspergillus nidulans
expressed in Saccharomyces cerevisiae Yarrowia lipolytica
expressed in Saccharomyces cerevisiae Lipomyces starkeyi
expressed in Saccharomyces cerevisiae Rhodotorula toruloides

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-
cytosol
-
 Aspergillus nidulans 5829
-
cytosol
-
 Yarrowia lipolytica 5829
-
cytosol
-
 Lipomyces starkeyi 5829
-
cytosol
-
 Rhodotorula toruloides 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + phosphate + acetyl-CoA + oxaloacetate Mus musculus
-
 ATP + citrate + CoA
-
 ?
ADP + phosphate + acetyl-CoA + oxaloacetate Aspergillus nidulans
-
 ATP + citrate + CoA
-
 ?
ADP + phosphate + acetyl-CoA + oxaloacetate Yarrowia lipolytica
-
 ATP + citrate + CoA
-
 ?
ADP + phosphate + acetyl-CoA + oxaloacetate Lipomyces starkeyi
-
 ATP + citrate + CoA
-
 ?
ADP + phosphate + acetyl-CoA + oxaloacetate Rhodotorula toruloides
-
 ATP + citrate + CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus nidulans
-
-
-
Lipomyces starkeyi
-
-
-
Mus musculus
-
-
-
Rhodotorula toruloides
-
-
-
Yarrowia lipolytica
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + phosphate + acetyl-CoA + oxaloacetate
-
 Mus musculus ATP + citrate + CoA
-
 ?
ADP + phosphate + acetyl-CoA + oxaloacetate
-
 Aspergillus nidulans ATP + citrate + CoA
-
 ?
ADP + phosphate + acetyl-CoA + oxaloacetate
-
 Yarrowia lipolytica ATP + citrate + CoA
-
 ?
ADP + phosphate + acetyl-CoA + oxaloacetate
-
 Lipomyces starkeyi ATP + citrate + CoA
-
 ?
ADP + phosphate + acetyl-CoA + oxaloacetate
-
 Rhodotorula toruloides ATP + citrate + CoA
-
 ?

Synonyms

Synonyms Comment Organism
ACL
-
 Mus musculus
ACL
-
 Aspergillus nidulans
ACL
-
 Yarrowia lipolytica
ACL
-
 Lipomyces starkeyi
ACL
-
 Rhodotorula toruloides
ATP citrate lyase
-
 Mus musculus
ATP citrate lyase
-
 Aspergillus nidulans
ATP citrate lyase
-
 Yarrowia lipolytica
ATP citrate lyase
-
 Lipomyces starkeyi
ATP citrate lyase
-
 Rhodotorula toruloides