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Literature summary for 2.3.3.8 extracted from
- ADP-Mg2+ bound to the ATP-grasp domain of ATP-citrate lyase (2011), Acta Crystallogr. Sect. F, 67, 1168-1172.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| tartrate and ADP-Mg2+ bound N-terminal portion of the enzyme containing residues 1-817, hanging drop vapor diffusion method, using 12.5% (w/v) polyethylene glycol 3350, 125 mM sodium tartrate, 100 mM Tris-HCl (pH 8.2) | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Tartrate | - |
Homo sapiens |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Homo sapiens | 5737 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P53396 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| immobilized metal-ion affinity chromatography | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + citrate + CoA | - |
Homo sapiens | ADP + phosphate + acetyl-CoA + oxaloacetate | - |
ir | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ACLY | - |
Homo sapiens |
| ATP-citrate lyase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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