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Literature summary for 2.3.3.8 extracted from

  • Wells, T.N.C.
    ATP-citrate lyase from rat liver. Characterisation of the citryl-enzyme complexes (1991), Eur. J. Biochem., 199, 163-168.
    View publication on PubMed
Search for more literature for 2.3.3.8

General Stability

General Stability Organism
ATP and citrate stabilize Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Reaction

Reaction Comment Organism Reaction ID
ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA mechanism Rattus norvegicus
a
ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA in the absence of the CoA acceptor, the enzyme contains a freely diffusible highly reactive intermediate, with similar properties to other high-free-energy phosphotransfer intermediates such as aminoacyl adenylates Rattus norvegicus
a

Source Tissue

Source Tissue Comment Organism Textmining

Storage Stability

Storage Stability Organism
-20°C, stable Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + citrate + CoA
-
 Rattus norvegicus ADP + phosphate + acetyl-CoA + oxaloacetate
-
 ?