Literature summary for 2.3.3.13 extracted from

He, Y.; Cheng, J.; He, Y.; Yang, B.; Cheng, Y.; Yang, C.; Zhang, H.; Wang, Z.
Influence of isopropylmalate synthase OsIPMS1 on seed vigour associated with amino acid and energy metabolism in rice (2019), Plant Biotechnol. J., 17, 322-337 .

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Application

Application	Comment	Organism
agriculture	the OsIPMS1 might be used as a biomarker to determine the best stop time-point of seed priming in rice	Oryza sativa Japonica Group

Inhibitors

Inhibitors	Comment	Organism	Structure
leucine	-	Oryza sativa Japonica Group

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
acetyl-CoA + 3-methyl-2-oxobutanoate + H2O	Oryza sativa Japonica Group	the enzyme catalyses the committed step of leucine biosynthesis	(2S)-2-isopropylmalate + CoA	-	?

Organism

Organism	UniProt	Comment	Textmining
Oryza sativa Japonica Group	Q2QXY9	-	-
Oryza sativa Japonica Group	Q2RAP8	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
seed	-	Oryza sativa Japonica Group	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acetyl-CoA + 3-methyl-2-oxobutanoate + H2O	-	Oryza sativa Japonica Group	(2S)-2-isopropylmalate + CoA	-	?
acetyl-CoA + 3-methyl-2-oxobutanoate + H2O	the enzyme catalyses the committed step of leucine biosynthesis	Oryza sativa Japonica Group	(2S)-2-isopropylmalate + CoA	-	?

Synonyms

Synonyms	Comment	Organism
Os11g04670	locus name	Oryza sativa Japonica Group
Os12g04440	locus name	Oryza sativa Japonica Group
OsIPMS1	-	Oryza sativa Japonica Group
OsIPMS2	-	Oryza sativa Japonica Group

Expression

Organism	Comment	Expression
Oryza sativa Japonica Group	transcripts of OsIPMS1 and OsIPMS2 are significantly increased in the filling grain from 0 to 7 days after flowering and then sharply decreases after the 14th day after flowering	down
Oryza sativa Japonica Group	transcripts of OsIPMS1 and OsIPMS2 are significantly increased in the filling grain from 0 to 7 days after flowering and then sharply decreases after the 14th day after flowering. The transcript is strongly detected at 48-h imbibition when seeds begin germinating	up
Oryza sativa Japonica Group	transcripts of OsIPMS1 and OsIPMS2 are significantly increased in the filling grain from 0 to 7 days after flowering and then sharply decreases after the 14th day after flowering. The transcript was strongly detected at 48-h imbibition when seeds begin germinating	up

General Information

General Information	Comment	Organism
malfunction	disruption of OsIPMS1 results in low seed vigour under various conditions, which might be tightly associated with the reduction of amino acids in germinating seeds. Eleven amino acids that associated with stress tolerance, GA biosynthesis and tricarboxylic acid cycle are significantly reduced in osipms1 mutants compared with those in wide type during seed germination. Transcriptome analysis indicates that a total of 1209 differentially expressed genes are altered in osipms1a mutant compared with wilde type at the early germination stage, wherein most of the genes were involved in glycolysis/gluconeogenesis, protein processing, pyruvate, carbon, fructose and mannose metabolism	Oryza sativa Japonica Group
metabolism	the enzyme catalyses the committed step of leucine biosynthesis	Oryza sativa Japonica Group
metabolism	the enzyme catalyses the committed step of leucine biosynthesis. The regulation of OsIPMS1 in seed vigour is involved in starch hydrolysis, glycolytic activity and energy levels in germinating seeds. The effects of seed priming are tightly associated with the mRNA levels of OsIPMS1 in priming seeds	Oryza sativa Japonica Group

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Release 2023.1 (January 2023)