Inhibitors | Comment | Organism | Structure |
---|---|---|---|
leucine | - |
Hydrogenomonas sp. | |
leucine | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Salmonella enterica subsp. enterica serovar Typhimurium | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Bacillus subtilis | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Escherichia coli | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Cereibacter sphaeroides | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Bradyrhizobium japonicum | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Pseudomonas fluorescens | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Klebsiella aerogenes | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Pseudomonas aeruginosa | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Proteus vulgaris | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Micrococcus luteus | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Paenibacillus polymyxa | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Chromatium sp. | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Rhodococcus opacus | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Micrococcus sp. | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Methylorubrum extorquens | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Alcaligenes viscolactis | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Hydrogenomonas sp. | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Chromatium sp. D | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Escherichia coli B / ATCC 11303 | first enzyme in biosynthesis of L-Leu | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Alcaligenes viscolactis | - |
- |
- |
Bacillus subtilis | - |
- |
- |
Bradyrhizobium japonicum | - |
- |
- |
Cereibacter sphaeroides | - |
- |
- |
Chromatium sp. | - |
- |
- |
Chromatium sp. D | - |
- |
- |
Escherichia coli | - |
- |
- |
Escherichia coli B / ATCC 11303 | - |
- |
- |
Hydrogenomonas sp. | - |
- |
- |
Klebsiella aerogenes | - |
- |
- |
Methylorubrum extorquens | - |
- |
- |
Micrococcus luteus | - |
- |
- |
Micrococcus sp. | - |
- |
- |
Paenibacillus polymyxa | - |
- |
- |
Proteus vulgaris | - |
- |
- |
Pseudomonas aeruginosa | - |
- |
- |
Pseudomonas fluorescens | - |
- |
- |
Rhodococcus opacus | - |
- |
- |
Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Bacillus subtilis | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Escherichia coli | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Cereibacter sphaeroides | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Bradyrhizobium japonicum | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Pseudomonas fluorescens | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Klebsiella aerogenes | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Pseudomonas aeruginosa | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Proteus vulgaris | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Micrococcus luteus | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Paenibacillus polymyxa | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Chromatium sp. | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Rhodococcus opacus | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Micrococcus sp. | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Methylorubrum extorquens | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Alcaligenes viscolactis | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Hydrogenomonas sp. | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Chromatium sp. D | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Escherichia coli B / ATCC 11303 | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Salmonella enterica subsp. enterica serovar Typhimurium | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Bacillus subtilis | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Escherichia coli | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Cereibacter sphaeroides | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Bradyrhizobium japonicum | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Pseudomonas fluorescens | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Klebsiella aerogenes | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Pseudomonas aeruginosa | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Proteus vulgaris | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Micrococcus luteus | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Paenibacillus polymyxa | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Chromatium sp. | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Rhodococcus opacus | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Micrococcus sp. | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Methylorubrum extorquens | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Alcaligenes viscolactis | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Hydrogenomonas sp. | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Chromatium sp. D | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Escherichia coli B / ATCC 11303 | ? | - |
? |