Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5',5',5'-trifluoroleucine | - |
Hydrogenomonas sp. | |
leucine | non-competitive, sensitivity is maximal at pH 7.2 and negligible at pH 8.4 | Hydrogenomonas sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Hydrogenomonas sp. | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Hydrogenomonas sp. | repression by Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Hydrogenomonas sp. H16 | first enzyme in biosynthesis of L-Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Hydrogenomonas sp. H16 | repression by Leu | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hydrogenomonas sp. | - |
- |
- |
Hydrogenomonas sp. H16 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Hydrogenomonas sp. | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Hydrogenomonas sp. H16 | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Hydrogenomonas sp. | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | repression by Leu | Hydrogenomonas sp. | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | first enzyme in biosynthesis of L-Leu | Hydrogenomonas sp. H16 | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | repression by Leu | Hydrogenomonas sp. H16 | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.4 | - |
- |
Hydrogenomonas sp. |