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Literature summary for 2.3.3.13 extracted from

  • Hampsey, D.M.; Lewin, A.S.; Kohlhaw, G.B.
    Submitochondrial localization, cell-free synthesis, and mitochondrial import of 2-isopropylmalate synthase of yeast (1983), Proc. Natl. Acad. Sci. USA, 80, 1270-1274.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion large enzyme form, matrix Saccharomyces cerevisiae 5739
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Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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and strain S288c
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Saccharomyces cerevisiae D273-10B
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and strain S288c
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-oxo-3-methylbutanoate + acetyl-CoA + H2O
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Saccharomyces cerevisiae 3-hydroxy-4-methyl-3-carboxypentanoate + CoA i.e. alpha-isopropylmalate ?
2-oxo-3-methylbutanoate + acetyl-CoA + H2O
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Saccharomyces cerevisiae D273-10B 3-hydroxy-4-methyl-3-carboxypentanoate + CoA i.e. alpha-isopropylmalate ?