Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | the addition of 5 mM valine plus isoleucine with and without 5 mM threonine caused a 4-6.6fold increase in the formation of active enzyme | Cupriavidus necator |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Cupriavidus necator | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Cupriavidus necator | the enzyme is regulated by the level of Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Cupriavidus necator | involved in Leu biosynthesis | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Cupriavidus necator H 16 | the enzyme is regulated by the level of Leu | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | Cupriavidus necator H 16 | involved in Leu biosynthesis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cupriavidus necator | - |
- |
- |
Cupriavidus necator H 16 | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
culture condition:acetate-grown cell | unusually high specific activity of enzyme | Cupriavidus necator | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Cupriavidus necator | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | - |
Cupriavidus necator H 16 | 3-hydroxy-4-methyl-3-carboxypentanoate + CoA | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | the enzyme is regulated by the level of Leu | Cupriavidus necator | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | involved in Leu biosynthesis | Cupriavidus necator | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | the enzyme is regulated by the level of Leu | Cupriavidus necator H 16 | ? | - |
? | |
2-oxo-3-methylbutanoate + acetyl-CoA + H2O | involved in Leu biosynthesis | Cupriavidus necator H 16 | ? | - |
? |