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Literature summary for 2.3.3.10 extracted from

  • Tao, T.; Chen, Q.; Meng, X.; Yan, J.; Xu, F.; Chang, J.
    Molecular cloning, characterization, and functional analysis of a gene encoding 3-hydroxy-3-methylglutaryl-coenzyme A synthase from Matricaria chamomilla (2016), Genes Genomics, 38, 1179-1187 .
No PubMed abstract available
Search for more literature for 2.3.3.10

Cloned(Commentary)

Cloned (Comment) Organism
-
 Matricaria chamomilla

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
50700
-
 calculated from sequence Matricaria chamomilla

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + H2O + acetoacetyl-CoA Matricaria chamomilla first committed enzyme in the mevalonate pathway. The enzyme plays an important role in the biosynthesis of the sesquiterpene, which is the main constituent of essential oil in Matricaria chamomilla (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Matricaria chamomilla A0A140GL77
-
-

Source Tissue

Source Tissue Comment Organism Textmining
flower predominantly expressed in flowers Matricaria chamomilla
-
leaf
-
 Matricaria chamomilla
-
root
-
 Matricaria chamomilla
-
stem
-
 Matricaria chamomilla
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + H2O + acetoacetyl-CoA
-
 Matricaria chamomilla (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?
acetyl-CoA + H2O + acetoacetyl-CoA first committed enzyme in the mevalonate pathway. The enzyme plays an important role in the biosynthesis of the sesquiterpene, which is the main constituent of essential oil in Matricaria chamomilla Matricaria chamomilla (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
-
 ?

Synonyms

Synonyms Comment Organism
3-hydroxy-3-methylglutaryl-coenzyme A synthase
-
 Matricaria chamomilla
HMGS
-
 Matricaria chamomilla

pI Value

Organism Comment pI Value Maximum pI Value
Matricaria chamomilla calculated from sequence
-
 5.69

Expression

Organism Comment Expression
Matricaria chamomilla induced by methyl jasmonate. The transcript level increases gradually and reaches maximum (5.6fold higher than the control) at 24 h after methyl jasmonate treatment. Thereafter, the transcript level declines but is still significant higher than those of control from 48 to 96 h posttreatment of methyl jasmonate. At 96 h, a 2.4fold increase in expression compared to control is observed up

General Information

General Information Comment Organism
metabolism first committed enzyme in the mevalonate pathway. The enzyme plays an important role in the biosynthesis of the sesquiterpene, which is the main constituent of essential oil in Matricaria chamomilla Matricaria chamomilla