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Literature summary for 2.3.2.B23 extracted from

  • Zhang, Y.; Yao, T.; Jiang, Y.; Li, H.; Yuan, W.; Li, W.
    Deciphering a cyclodipeptide synthase pathway encoding prenylated indole alkaloids in Streptomyces leeuwenhoekii (2021), Appl. Environ. Microbiol., 87, e02525.
    View publication on PubMed
Search for more literature for 2.3.2.B23

Cloned(Commentary)

Cloned (Comment) Organism
expression in Streptomyces albus J1074 Streptomyces leeuwenhoekii

Organism

Organism UniProt Comment Textmining
Streptomyces leeuwenhoekii
-
-
-
Streptomyces leeuwenhoekii NRRL B-24963
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophanyl-tRNATrp + L-tryptophanyl-tRNATrp
-
 Streptomyces leeuwenhoekii 2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl)
-
 ?
L-tryptophanyl-tRNATrp + L-tryptophanyl-tRNATrp
-
 Streptomyces leeuwenhoekii NRRL B-24963 2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl)
-
 ?

Synonyms

Synonyms Comment Organism
SazA
-
 Streptomyces leeuwenhoekii

General Information

General Information Comment Organism
physiological function expression of CDPS SazA and of SazB harboring fused domains: phytoene synthase-like prenyltransferase and methyltransferase, in Streptomyces albus J1074 leads to the production of four prenylated indole alkaloids, including streptoazines A to C. SazA catalyzes the formation of cyclo(L-Trp-L-Trp) Streptomyces leeuwenhoekii