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Literature summary for 2.3.2.B23 extracted from
- Production of diketopiperazine derivatives by pathway engineering with different cyclodipeptide synthases from various Streptomyces strains (2023), ACS Synth. Biol., 12, 1804-1812.
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | expression of CDPS and genes gtmB-gtmE for tailoring enzymes from Streptomyces cinnamoneus enables the synthesis of modified cyclodipeptides | Streptomyces monomycini |
| synthesis | expression of CDPS and genes gtmB-gtmE for tailoring enzymes from Streptomyces cinnamoneus enables the synthesis of modified cyclodipeptides | Streptomyces varsoviensis |
| synthesis | expression of CDPS and genes gtmB-gtmE for tailoring enzymes from Streptomyces cinnamoneus enables the synthesis of modified cyclodipeptides | Streptomyces sp. NRRL F-5053 |
| synthesis | expression of CDPS and genes gtmB-gtmE for tailoring enzymes from Streptomyces cinnamoneus enables the synthesis of modified cyclodipeptides | Streptomyces sp. NRRL S-1868 |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptomyces monomycini | - |
- |
- |
| Streptomyces monomycini NRRL B-24309 | - |
- |
- |
| Streptomyces sp. NRRL F-5053 | - |
- |
- |
| Streptomyces sp. NRRL S-1868 | - |
- |
- |
| Streptomyces varsoviensis | - |
- |
- |
| Streptomyces varsoviensis NRRL B-3589 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tryptophanyl-tRNATrp + L-alanyl-tRNAAla | - |
Streptomyces sp. NRRL S-1868 | tRNATrp + tRNAAla + cyclo(L-tryptophanyl-L-alanyl) | - |
? |  |
| L-tryptophanyl-tRNATrp + L-leucyl-tRNALeu | - |
Streptomyces sp. NRRL F-5053 | tRNATrp + tRNALeu + cyclo(L-tryptophanyl-L-leucyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-phenylalanyl-tRNAPhe | - |
Streptomyces monomycini | tRNATrp + tRNAPhe + cyclo(L-tryptophanyl-L-phenylalanyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-phenylalanyl-tRNAPhe | - |
Streptomyces varsoviensis | tRNATrp + tRNAPhe + cyclo(L-tryptophanyl-L-phenylalanyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-phenylalanyl-tRNAPhe | - |
Streptomyces monomycini NRRL B-24309 | tRNATrp + tRNAPhe + cyclo(L-tryptophanyl-L-phenylalanyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-phenylalanyl-tRNAPhe | - |
Streptomyces varsoviensis NRRL B-3589 | tRNATrp + tRNAPhe + cyclo(L-tryptophanyl-L-phenylalanyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | - |
Streptomyces sp. NRRL S-1868 | tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-tyrosyl-tRNATyr | - |
Streptomyces varsoviensis | tRNATrp + tRNATyr + cyclo(L-tryptophanyl-L-tyrosyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-tyrosyl-tRNATyr | - |
Streptomyces varsoviensis NRRL B-3589 | tRNATrp + tRNATyr + cyclo(L-tryptophanyl-L-tyrosyl) | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ASPA | - |
Streptomyces sp. NRRL S-1868 |
| CWLS1 | - |
Streptomyces sp. NRRL F-5053 |
| GutA24309 | - |
Streptomyces monomycini |
| GutA3589 | - |
Streptomyces varsoviensis |
| NasA | - |
Streptomyces sp. NRRL S-1868 |
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