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Literature summary for 2.3.2.B16 extracted from
- Expanding tryptophan-containing cyclodipeptide synthase spectrum by identification of nine members from Streptomyces strains (2018), Appl. Microbiol. Biotechnol., 102, 4435-4444 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene SCATT_09020, phylogenetic analysis, recombinant overexpression in Escherichia coli | Streptomyces cattleya |
| gene SCATT_42550, phylogenetic analysis, recombinant overexpression in Escherichia coli | Streptomyces cattleya |
| gene SLAV_12475, phylogenetic analysis, recombinant overexpression in Escherichia coli | Streptomyces lavendulae |
| phylogenetic analysis, recombinant overexpression in Escherichia coli | Streptomyces purpureus |
| phylogenetic analysis, recombinant overexpression in Escherichia coli | Streptomyces sp. NRRL S-1868 |
| recombinant overexpression in Escherichia coli | Streptomyces xanthophaeus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2 L-tryptophanyl-tRNATrp | Streptomyces purpureus | - |
2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl) | - |
? |  |
| 2 L-tryptophanyl-tRNATrp | Streptomyces xanthophaeus | - |
2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl) | - |
? | |
| 2 L-tryptophanyl-tRNATrp | Streptomyces sp. NRRL S-1868 | - |
2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl) | - |
? | |
| 2 L-tryptophanyl-tRNATrp | Streptomyces xanthophaeus NRRL B-5414 | - |
2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl) | - |
? | |
| 2 L-tryptophanyl-tRNATrp | Streptomyces purpureus NRRL B-5737 | - |
2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-alanyl-tRNAAla | Streptomyces sp. NRRL S-1868 | - |
tRNATrp + tRNAAla + cyclo(L-tryptophanyl-L-alanyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-leucyl-tRNALeu | Streptomyces cattleya | - |
tRNATrp + tRNALeu + cyclo(L-tryptophanyl-L-leucyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-leucyl-tRNALeu | Streptomyces cattleya ATCC 35852 | - |
tRNATrp + tRNALeu + cyclo(L-tryptophanyl-L-leucyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-leucyl-tRNALeu | Streptomyces cattleya NRRL 8057 | - |
tRNATrp + tRNALeu + cyclo(L-tryptophanyl-L-leucyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-leucyl-tRNALeu | Streptomyces cattleya DSM 46488 | - |
tRNATrp + tRNALeu + cyclo(L-tryptophanyl-L-leucyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-leucyl-tRNALeu | Streptomyces cattleya JCM 4925 | - |
tRNATrp + tRNALeu + cyclo(L-tryptophanyl-L-leucyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-leucyl-tRNALeu | Streptomyces cattleya NBRC 14057 | - |
tRNATrp + tRNALeu + cyclo(L-tryptophanyl-L-leucyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | Streptomyces cattleya | - |
tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | Streptomyces lavendulae | - |
tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | Streptomyces sp. NRRL S-1868 | - |
tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | Streptomyces cattleya ATCC 35852 | - |
tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | Streptomyces cattleya NRRL 8057 | - |
tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | Streptomyces lavendulae NRRL B-2774 | - |
tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | Streptomyces cattleya DSM 46488 | - |
tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | Streptomyces cattleya JCM 4925 | - |
tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | Streptomyces cattleya NBRC 14057 | - |
tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptomyces cattleya | F8JRC6 | - |
- |
| Streptomyces cattleya | F8JX03 | - |
- |
| Streptomyces cattleya ATCC 35852 | F8JRC6 | - |
- |
| Streptomyces cattleya ATCC 35852 | F8JX03 | - |
- |
| Streptomyces cattleya DSM 46488 | F8JRC6 | - |
- |
| Streptomyces cattleya DSM 46488 | F8JX03 | - |
- |
| Streptomyces cattleya JCM 4925 | F8JRC6 | - |
- |
| Streptomyces cattleya JCM 4925 | F8JX03 | - |
- |
| Streptomyces cattleya NBRC 14057 | F8JRC6 | - |
- |
| Streptomyces cattleya NBRC 14057 | F8JX03 | - |
- |
| Streptomyces cattleya NRRL 8057 | F8JRC6 | - |
- |
| Streptomyces cattleya NRRL 8057 | F8JX03 | - |
- |
| Streptomyces lavendulae | A0A2K8PC82 | - |
- |
| Streptomyces lavendulae NRRL B-2774 | A0A2K8PC82 | - |
- |
| Streptomyces purpureus | - |
- |
- |
| Streptomyces purpureus NRRL B-5737 | - |
- |
- |
| Streptomyces sp. NRRL S-1868 | - |
- |
- |
| Streptomyces xanthophaeus | - |
- |
- |
| Streptomyces xanthophaeus NRRL B-5414 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2 L-tryptophanyl-tRNATrp | - |
Streptomyces purpureus | 2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl) | - |
? | |
| 2 L-tryptophanyl-tRNATrp | - |
Streptomyces xanthophaeus | 2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl) | - |
? | |
| 2 L-tryptophanyl-tRNATrp | - |
Streptomyces sp. NRRL S-1868 | 2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl) | - |
? | |
| 2 L-tryptophanyl-tRNATrp | - |
Streptomyces xanthophaeus NRRL B-5414 | 2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl) | - |
? | |
| 2 L-tryptophanyl-tRNATrp | - |
Streptomyces purpureus NRRL B-5737 | 2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-alanyl-tRNAAla | - |
Streptomyces sp. NRRL S-1868 | tRNATrp + tRNAAla + cyclo(L-tryptophanyl-L-alanyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-leucyl-tRNALeu | - |
Streptomyces cattleya | tRNATrp + tRNALeu + cyclo(L-tryptophanyl-L-leucyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-leucyl-tRNALeu | - |
Streptomyces cattleya ATCC 35852 | tRNATrp + tRNALeu + cyclo(L-tryptophanyl-L-leucyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-leucyl-tRNALeu | - |
Streptomyces cattleya NRRL 8057 | tRNATrp + tRNALeu + cyclo(L-tryptophanyl-L-leucyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-leucyl-tRNALeu | - |
Streptomyces cattleya DSM 46488 | tRNATrp + tRNALeu + cyclo(L-tryptophanyl-L-leucyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-leucyl-tRNALeu | - |
Streptomyces cattleya JCM 4925 | tRNATrp + tRNALeu + cyclo(L-tryptophanyl-L-leucyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-leucyl-tRNALeu | - |
Streptomyces cattleya NBRC 14057 | tRNATrp + tRNALeu + cyclo(L-tryptophanyl-L-leucyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | - |
Streptomyces cattleya | tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | - |
Streptomyces lavendulae | tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | - |
Streptomyces sp. NRRL S-1868 | tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | - |
Streptomyces cattleya ATCC 35852 | tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | - |
Streptomyces cattleya NRRL 8057 | tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | - |
Streptomyces lavendulae NRRL B-2774 | tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | - |
Streptomyces cattleya DSM 46488 | tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | - |
Streptomyces cattleya JCM 4925 | tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
| L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro | - |
Streptomyces cattleya NBRC 14057 | tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl) | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CDPS | - |
Streptomyces purpureus |
| CDPS | - |
Streptomyces cattleya |
| CDPS | - |
Streptomyces lavendulae |
| CDPS | - |
Streptomyces xanthophaeus |
| CDPS | - |
Streptomyces sp. NRRL S-1868 |
| CWPS1NS1868 | - |
Streptomyces sp. NRRL S-1868 |
| CWWS1D46488 | - |
Streptomyces cattleya |
| CWWS1NB2774 | - |
Streptomyces lavendulae |
| CWWS1NB5414 | - |
Streptomyces xanthophaeus |
| CWWS1NB5737 | - |
Streptomyces purpureus |
| CWWS2D46488 | - |
Streptomyces cattleya |
| cyclo-(L-Trp-L-Leu) synthase | - |
Streptomyces cattleya |
| cyclo-(L-Trp-L-Pro) synthase | - |
Streptomyces cattleya |
| cyclo-(L-Trp-L-Pro) synthase | - |
Streptomyces lavendulae |
| cyclo-(L-Trp-L-Trp) synthase | - |
Streptomyces purpureus |
| cyclo-(L-Trp-L-Trp) synthase | - |
Streptomyces xanthophaeus |
| cyclo-(L-Trp-L-Trp) synthase | - |
Streptomyces sp. NRRL S-1868 |
| cyclodipeptide synthase | - |
Streptomyces purpureus |
| cyclodipeptide synthase | - |
Streptomyces cattleya |
| cyclodipeptide synthase | - |
Streptomyces lavendulae |
| cyclodipeptide synthase | - |
Streptomyces xanthophaeus |
| cyclodipeptide synthase | - |
Streptomyces sp. NRRL S-1868 |
General Information
| General Information | Comment | Organism |
|---|---|---|
| evolution | phylogenetic analysis of tryptophan-containing cyclodipeptide synthases | Streptomyces purpureus |
| evolution | phylogenetic analysis of tryptophan-containing cyclodipeptide synthases | Streptomyces cattleya |
| evolution | phylogenetic analysis of tryptophan-containing cyclodipeptide synthases | Streptomyces lavendulae |
| evolution | phylogenetic analysis of tryptophan-containing cyclodipeptide synthases | Streptomyces sp. NRRL S-1868 |
| physiological function | the enzyme is a tryptophan-containing cyclodipeptide synthase | Streptomyces purpureus |
| physiological function | the enzyme is a tryptophan-containing cyclodipeptide synthase | Streptomyces cattleya |
| physiological function | the enzyme is a tryptophan-containing cyclodipeptide synthase | Streptomyces lavendulae |
| physiological function | the enzyme is a tryptophan-containing cyclodipeptide synthase | Streptomyces xanthophaeus |
| physiological function | the enzyme is a tryptophan-containing cyclodipeptide synthase | Streptomyces sp. NRRL S-1868 |
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