Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2'-(1-amino ethyl phosphonyl) adenosine | 1 mM, 55% inhibition | Streptococcus pneumoniae | |
3'-(1-amino ethyl phosphonyl) 2'-deoxyadenosine | 1 mM, 95% inhibition | Streptococcus pneumoniae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus pneumoniae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ditrans,ocatacis-undecaprenyl diphosphoryl (GlcNAc-beta-(1->4))MurNAc-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-Ala-tRNa | - |
Streptococcus pneumoniae | ditrans,ocatacis-undecaprenyl diphosphoryl (GlcNAc-beta-(1->4))MurNAc-L-alanyl-gamma-D-glutamyl-L-lysyl(N6-L-alanyl)-D-alanyl-D-alanine + tRNA | - |
? |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.1 | - |
pH 6.8, 37°C | Streptococcus pneumoniae | 3'-(1-amino ethyl phosphonyl) 2'-deoxyadenosine | |
0.78 | - |
pH 6.8, 37°C | Streptococcus pneumoniae | 2'-(1-amino ethyl phosphonyl) adenosine |