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Literature summary for 2.3.2.32 extracted from

  • Kurz, T.; Özlü, N.; Rudolf, F.; ORourke, S.; Luke, B.; Hofmann, K.; Hyman, A.; Bowerman, B.; Peter, M.
    The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae (2005), Nature, 435, 1257-1261 .
    View publication on PubMed
Search for more literature for 2.3.2.32

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin Cdc53]-L-lysine Saccharomyces cerevisiae
-
 [E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin Cdc53]-N6-[NEDD8-protein]-yl-L-lysine
-
 ?
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin Cdc53]-L-lysine Caenorhabditis elegans
-
 [E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin Cdc53]-N6-[NEDD8-protein]-yl-L-lysine
-
 ?

Organism

Organism UniProt Comment Textmining
Caenorhabditis elegans
-
 Bristol strain N2
-
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin Cdc53]-L-lysine
-
 Saccharomyces cerevisiae [E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin Cdc53]-N6-[NEDD8-protein]-yl-L-lysine
-
 ?
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin Cdc53]-L-lysine
-
 Caenorhabditis elegans [E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin Cdc53]-N6-[NEDD8-protein]-yl-L-lysine
-
 ?

Subunits

Subunits Comment Organism
? x * 83000, SDS-PAGE Saccharomyces cerevisiae
? x * 83000, SDS-PAGE Caenorhabditis elegans

Synonyms

Synonyms Comment Organism
DCN-1
-
 Caenorhabditis elegans
Dcn1p
-
 Saccharomyces cerevisiae