Literature summary for 2.3.2.32 extracted from

Rahighi, S.; Dikic, I.
Conformational flexibility and rotation of the RING domain in activation of cullin-RING ligases (2011), Nat. Struct. Mol. Biol., 18, 863-865 .

No PubMed abstract available

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 1]-L-lysine720	Homo sapiens	-	[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 1]-N6-[NEDD8-protein]-yl-L-lysine720	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 1]-L-lysine720	-	Homo sapiens	[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 1]-N6-[NEDD8-protein]-yl-L-lysine720	-	?

Synonyms

Synonyms	Comment	Organism
RBX-1	-	Homo sapiens

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Release 2023.1 (January 2023)