Literature summary for 2.3.2.32 extracted from

Sakata, E.; Yamaguchi, Y.; Miyauchi, Y.; Iwai, K.; Chiba, T.; Saeki, Y.; Matsuda, N.; Tanaka, K.; Kato, K.
Direct interactions between NEDD8 and ubiquitin E2 conjugating enzymes upregulate cullin-based E3 ligase activity (2007), Nat. Struct. Mol. Biol., 14, 167-168 .

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin-1]-L-lysine	Homo sapiens	-	[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin-1]-N6-[NEDD8-protein]-yl-L-lysine	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin-1]-L-lysine	-	Homo sapiens	[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin-1]-N6-[NEDD8-protein]-yl-L-lysine	-	?

Synonyms

Synonyms	Comment	Organism
RBX1	-	Homo sapiens
ROC1	-	Homo sapiens

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Release 2023.1 (January 2023)