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Literature summary for 2.3.2.32 extracted from

  • Onel, M.; Sumbul, F.; Liu, J.; Nussinov, R.; Haliloglu, T.
    Cullin neddylation may allosterically tune polyubiquitin chain length and topology (2017), Biochem. J., 474, 781-795 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine Homo sapiens
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[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P62877
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine
-
Homo sapiens [E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine
-
?

Synonyms

Synonyms Comment Organism
RBX1
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Homo sapiens