Any feedback?
Literature summary for 2.3.2.3 extracted from
- Alanyl-phosphatidylglycerol and lysyl-phosphatidylglycerol are translocated by the same MprF flippases and have similar capacities to protect against the antibiotic daptomycin in Staphylococcus aureus (2012), Antimicrob. Agents Chemother., 56, 3492-3497.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in a Staphylococcus aureus mprF deletion mutant | Clostridium perfringens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Clostridium perfringens | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MprF2 | the enzyme encompasses a lysyl-phosphatidylglycerol synthase and a lysyl-phosphatidylglycerol flippase domain | Clostridium perfringens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | MprF2-mediated lysyl-phosphatidylglycerol production confers cationic antimicrobial peptide susceptibility with 6fold decreased daptomycin susceptibility or 4fold decreased gallidermin and nisin susceptibility compared to the Staphylococcus aureus mprF deletion mutant | Clostridium perfringens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
