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Literature summary for 2.3.2.27 extracted from

  • Yang, C.W.; Gonzalez-Lamothe, R.; Ewan, R.A.; Rowland, O.; Yoshioka, H.; Shenton, M.; Ye, H.; ODonnell, E.; Jones, J.D.; Sadanandom, A.
    The E3 ubiquitin ligase activity of Arabidopsis PLANT U-BOX17 and its functional tobacco homolog ACRE276 are required for cell death and defense (2006), Plant Cell, 18, 1084-1098.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.2.27

Cloned(Commentary)

Cloned (Comment) Organism
expression in Eschericia coli Solanum lycopersicum
expression in Eschericia coli Nicotiana tabacum
expression in Eschericia coli Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q9C7R6 isoform PUB17
-
Nicotiana tabacum Q84QD7 isoform ACRE276
-
Solanum lycopersicum
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf isoform ACRE276 is transiently induced in wounded leaves Nicotiana tabacum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information isoform ACRE276 is an E3 ubiquitin ligase requiring an intact U-box domain Solanum lycopersicum ?
-
 ?
additional information isoform ACRE276 is an E3 ubiquitin ligase requiring an intact U-box domain Nicotiana tabacum ?
-
 ?
additional information isoform ACRE276 is an E3 ubiquitin ligase requiring an intact U-box domain Arabidopsis thaliana ?
-
 ?
[ACRE276-RING domain-E3-ubiquitin-carrier protein HubC5B]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine enzyme displays ubiquitination activity in the presence of yeast E1 and human E2 HubC5B Solanum lycopersicum [ACRE276-RING domain-E3-ubiquitin-carrier protein]-L-cysteine + [acceptor protein]-N6-ubiquitinyl-L-lysine
-
 ?
[ACRE276-RING domain-E3-ubiquitin-carrier protein HubC5B]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine enzyme displays ubiquitination activity in the presence of yeast E1 and human E2 HubC5B Nicotiana tabacum [ACRE276-RING domain-E3-ubiquitin-carrier protein]-L-cysteine + [acceptor protein]-N6-ubiquitinyl-L-lysine
-
 ?
[ACRE276-RING domain-E3-ubiquitin-carrier protein HubC5B]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine enzyme displays ubiquitination activity in the presence of yeast E1 and human E2 HubC5B Arabidopsis thaliana [ACRE276-RING domain-E3-ubiquitin-carrier protein]-L-cysteine + [acceptor protein]-N6-ubiquitinyl-L-lysine
-
 ?

Synonyms

Synonyms Comment Organism
ACRE276
-
 Solanum lycopersicum
ACRE276
-
 Nicotiana tabacum
Avr9/Cf-9 rapidly elicited protein 276
-
 Solanum lycopersicum
Avr9/Cf-9 rapidly elicited protein 276
-
 Nicotiana tabacum
PLANT U-BOX17
-
 Arabidopsis thaliana
PUB17
-
 Arabidopsis thaliana
U-box domain-containing protein 17
-
 Arabidopsis thaliana

Expression

Organism Comment Expression
Nicotiana tabacum expression of isoform ACRE276 is transiently induced in wounded leaves within 15 min, but upon Avr9 elicitor treatment, this upregulation is enhanced and maintained until cell death onset up

General Information

General Information Comment Organism
physiological function isoform ACRE276 RNA interference silencing in tobacco results in loss of hypersensitive response specified by Cf resistance genes. ACRE276 RNAi plants are also compromised for hypersensitive response mediated by the tobacco mosaic virus defense elicitor p50 Nicotiana tabacum
physiological function silencing isoform ACRE276 leads to breakdown of Cf-9–specified resistance against Cladosporium fulvum leaf mold Solanum lycopersicum
physiological function transient expression of isoform PUB17 in Cf-9 tobacco silenced for ubiquitin ligase ACRE276 restores hypersensitive response, while mutant PUB17 lacking E3 ligase activity fails to do so. PUB17 ligase activity is crucial for defense signaling. PUB17 knockout plants are compromised in RPM1- and RPS4-mediated resistance against Pseudomonas syringae pv tomato containing avirulence genes AvrB and AvrRPS4, respectively Arabidopsis thaliana