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Literature summary for 2.3.2.26 extracted from
- A new HECT ubiquitin ligase regulating chemotaxis and development in Dictyostelium discoideum (2017), J. Cell Sci., 130, 551-562 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Dictyostelium discoideum | Q54L33 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DDB_G0286931 | - |
Dictyostelium discoideum |
| HectPH1 | - |
Dictyostelium discoideum |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | inactivation of ubiquitin ligase HectPH1 is sufficient to reconstitute the parental phenotype of mutants defective in the TORC2 Pia subunit, which are impaired in chemotaxis and development. HectPH1 deletion rescues both chemotactic cell polarity and the underlying PKB phosphorylation and kinase activity of mutants defective in the TORC2 Pia subunit | Dictyostelium discoideum |
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Release 2023.1 (January 2023)
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