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Literature summary for 2.3.2.26 extracted from
- Identification of determinants in E2 ubiquitin-conjugating enzymes required for hect E3 ubiquitin-protein ligase interaction (1999), J. Biol. Chem., 274, 7576-7582.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q05086 | isoform E6-AP | - |
| Saccharomyces cerevisiae | P39940 | isoform RSP5 | - |
| Saccharomyces cerevisiae ATCC 204508 | P39940 | isoform RSP5 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | isoform E6-AP is loaded with ubiquitin by E2 enzyme UbcH5. A region of UbcH5 encompassing the catalytic site cysteine residue is critical for its ability to interact with E6-AP | Homo sapiens | ? | - |
? |  |
| additional information | isoform Rsp5 is loaded with ubiquitin by E2 enzyme UbcH5. A region of UbcH5 encompassing the catalytic site cysteine residue is critical for its ability to interact with RSP5 | Saccharomyces cerevisiae | ? | - |
? | |
| additional information | isoform Rsp5 is loaded with ubiquitin by E2 enzyme UbcH5. A region of UbcH5 encompassing the catalytic site cysteine residue is critical for its ability to interact with RSP5 | Saccharomyces cerevisiae ATCC 204508 | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| E6-AP | - |
Homo sapiens |
| RSP5 | - |
Saccharomyces cerevisiae |
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