Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
reticulocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | ubiquitin thiol ester forms of at least four of five E2s tested catalyze ubiquitin transfer to a number of small amines, in a reaction that does not require E3 enzyme, and only primary amines on primary carbons can serve as ubiquitin acceptors. E3-independent ubiquitin transfer to the small, basic proteins histones H2A and H2B, and cytochrome c, is also observed | Homo sapiens | ? | - |
? | |
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + L-lysine | - |
Homo sapiens | [E1 ubiquitin-activating enzyme]-L-cysteine + N6-monoubiquitinyl-L-lysine | - |
? | |
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [cytochrome c]-L-lysine | - |
Homo sapiens | [E1 ubiquitin-activating enzyme]-L-cysteine + N6-monoubiquitinyl-[cytochrome c]-L-lysine lysine | approximate relative activities as ubiquitin acceptors are: histones H2A:H2B:cytochrome c 1:0.5:0.2 | ? | |
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [histone H2A]-L-lysine | - |
Homo sapiens | [E1 ubiquitin-activating enzyme]-L-cysteine + N6-monoubiquitinyl-[histone H2A]-L-lysine | approximate relative activities as ubiquitin acceptors are: histones H2A:H2B:cytochrome c 1:0.5:0.2 | ? | |
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [histone H2B]-L-lysine | - |
Homo sapiens | [E1 ubiquitin-activating enzyme]-L-cysteine + N6-monoubiquitinyl-[histone H2B]-L-lysine lysine | approximate relative activities as ubiquitin acceptors are: histones H2A:H2B:cytochrome c 1:0.5:0.2 | ? |