Any feedback?
Please rate this page

BRENDA support

Literature summary for extracted from

  • Koenig, P.A.; Nicholls, P.K.; Schmidt, F.I.; Hagiwara, M.; Maruyama, T.; Frydman, G.H.; Watson, N.; Page, D.C.; Ploegh, H.L.
    The E2 ubiquitin-conjugating enzyme UBE2J1 is required for spermiogenesis in mice (2014), J. Biol. Chem., 289, 34490-34502.
    View publication on PubMedView publication on EuropePMC


Organism UniProt Comment Textmining
Mus musculus Q9JJZ4


Synonyms Comment Organism
Mus musculus
Mus musculus

General Information

General Information Comment Organism
physiological function Ube2J1-/- mice have reduced viability and fail to thrive early after birth. Male Ube2J1-/- mice are sterile due to a defect in late spermatogenesis. Removal of the cytoplasm is incomplete in Ube2J1-/- elongating spermatids, compromising the release of mature elongate spermatids into the lumen of the seminiferous tubule Mus musculus