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Literature summary for 2.3.2.23 extracted from
- HECT-E3 ligase ETC-1 regulates securin and cyclin B1 cytoplasmic abundance to promote timely anaphase during meiosis in C. elegans (2013), Development, 140, 2149-2159.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Caenorhabditis elegans | Q21633 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | HECT-E3 ligase ETC-1 ubiquitylates securin IFY-1 and cyclin B1 in the presence of the E2 enzyme UBC-18 | Caenorhabditis elegans | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Ubc-18 | - |
Caenorhabditis elegans |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | HECT-E3 ligase ETC-1 ubiquitylates securin IFY-1 and cyclin B1 in the presence of the E2 enzyme UBC-18, which functions in pharyngeal development. UBC-18 plays a distinct role together with ETC-1 in regulating the cytoplasmic level of IFY-1 during meiosis | Caenorhabditis elegans |
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