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Literature summary for 2.3.2.2 extracted from

  • Grzam, A.; Martin, M.N.; Hell, R.; Meyer, A.J.
    gamma-Glutamyl transpeptidase GGT4 initiates vacuolar degradation of glutathione S-conjugates in Arabidopsis (2007), FEBS Lett., 581, 3131-3138.
    View publication on PubMed
Search for more literature for 2.3.2.2

Inhibitors

Inhibitors Comment Organism Structure
acivicin
-
 Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
vacuole lumen Arabidopsis thaliana 5773
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Arabidopsis thaliana gamma-glutamyl transpeptidase 4 catalyzes the first step of vacuolar degradation of glutathione conjugates. Hydrolysis of glutathione S-bimane is blocked in ggt4 null mutants of Arabidopsis thaliana. Accumulation of glutathione S-bimane in mutants and in wild-type plants treated with the high affinity GGT inhibitor acivicin shows that GGT4 is required to initiate the two step hydrolysis sequence ?
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q9M0G0
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information gamma-glutamyl transpeptidase 4 catalyzes the first step of vacuolar degradation of glutathione conjugates. Hydrolysis of glutathione S-bimane is blocked in ggt4 null mutants of Arabidopsis thaliana. Accumulation of glutathione S-bimane in mutants and in wild-type plants treated with the high affinity GGT inhibitor acivicin shows that GGT4 is required to initiate the two step hydrolysis sequence Arabidopsis thaliana ?
-
 ?

Synonyms

Synonyms Comment Organism
gamma-glutamyl transpeptidase 4
-
 Arabidopsis thaliana
GGT4
-
 Arabidopsis thaliana