Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.2.13 extracted from

  • Fotschki, J.; Wroblewska, B.; Fotschki, B.; Kalicki, B.; Rigby, N.; Mackie, A.
    Microbial transglutaminase alters the immunogenic potential and cross-reactivity of horse and cow milk proteins (2020), J. Dairy Sci., 103, 2153-2166 .
    View publication on PubMed

Application

Application Comment Organism
additional information microbial transglutaminase alters the immunogenic potential and cross-reactivity of horse and cow milk proteins. Possibility of reducing the immunoreactivity of horse milk proteins by microbial transglutaminase (TG) polymerization. The diet based on modified horse milk proteins could be an alternative for some patients with cow milk protein allergy Streptomyces mobaraensis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-casein glutamine + alkylamine Streptomyces mobaraensis
-
alpha-casein N5-alkylglutamine + NH3
-
?
protein glutamine + alkylamine Streptomyces mobaraensis
-
protein N5-alkylglutamine + NH3
-
?

Organism

Organism UniProt Comment Textmining
Streptomyces mobaraensis P81453
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-casein glutamine + alkylamine
-
Streptomyces mobaraensis alpha-casein N5-alkylglutamine + NH3
-
?
additional information crosslinking activity and IgG reactivity after digestion with cow and horse milk proteins, detailed overview Streptomyces mobaraensis ?
-
-
protein glutamine + alkylamine
-
Streptomyces mobaraensis protein N5-alkylglutamine + NH3
-
?

Synonyms

Synonyms Comment Organism
microbial transglutaminase
-
Streptomyces mobaraensis

General Information

General Information Comment Organism
physiological function microbial transglutaminase alters the immunogenic potential and cross-reactivity of horse and cow milk proteins. The effect of TG on immunoreactivity depends on enzyme quantity and milk protein type. Determination of immunoreactivity of milk proteins by competitive ELISA Streptomyces mobaraensis