Literature summary for 2.3.2.13 extracted from

Pietroni, V.; Di Giorgi, S.; Paradisi, A.; Ahvazi, B.; Candi, E.; Melino, G.
Inactive and highly active, proteolytically processed transglutaminase-5 in epithelial cells (2008), J. Invest. Dermatol., 128, 2760-2766.

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Cloned(Commentary)

Cloned (Comment)	Organism
transfection of HaCat cell and HEK-293 cell	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
28000	-	x * 82000, full length protein, x * 53000 + x * 28000, proteolytically processed N-terminal active fragment and C-terminal regulatory domain, respectively	Homo sapiens
53000	-	x * 82000, full length protein, x * 53000 + x * 28000, proteolytically processed N-terminal active fragment and C-terminal regulatory domain, respectively	Homo sapiens
82000	-	x * 82000, full length protein, x * 53000 + x * 28000, proteolytically processed N-terminal active fragment and C-terminal regulatory domain, respectively	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
proteolytic modification	proteolytical processing of the 82000 Da full length protein to an N-terminal active 53000 Da fragment and a 28000 Da C-terminal regulatory domain. The full length enzyme shows low activity, while the 53000 Da form is highly active	Homo sapiens

Subunits

Subunits	Comment	Organism
?	x * 82000, full length protein, x * 53000 + x * 28000, proteolytically processed N-terminal active fragment and C-terminal regulatory domain, respectively	Homo sapiens

Synonyms

Synonyms	Comment	Organism
TG5	-	Homo sapiens

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Release 2023.1 (January 2023)