Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.2.12 extracted from

  • Erlacher, M.D.; Lang, K.; Shankaran, N.; Wotzel, B.; Huettenhofer, A.; Micura, R.; Mankin, A.S.; Polacek, N.
    Chemical engineering of the peptidyl transferase center reveals an important role of the 2-hydroxyl group of A2451 (2005), Nucleic Acids Res., 33, 1618-1627.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information mutations at base A2451 lead to strongly decreased enzyme activity Thermus aquaticus

Organism

Organism UniProt Comment Textmining
Thermus aquaticus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
AcPhe-tRNA + pCpCp-puromycin
-
Thermus aquaticus tRNA + AcPhe-pCpCp-puromycin
-
?

Synonyms

Synonyms Comment Organism
peptidyl transferase
-
Thermus aquaticus