Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-coumaroyl-CoA + quinate | Coleus scutellarioides | - |
CoA + 4-coumaroylquinate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Coleus scutellarioides | - |
syn. Solenostemon scutellarioides | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-coumaroyl-CoA + quinate | - |
Coleus scutellarioides | CoA + 4-coumaroylquinate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HQT | - |
Coleus scutellarioides |
hydroxycinnamoyl-CoA:quinate hydroxycinnamoyltransferase | - |
Coleus scutellarioides |
General Information | Comment | Organism |
---|---|---|
evolution | the enzyme belongs to the superfamily of BAHD acyltransferases. The conserved sequence motifs HxxxDG and DFGWG are surrounded by differing amino acid environments which show typical features for hydroxycinnamoyl-CoA:hydroxyphenyllactic acid hydroxycinnamoyltransferase, RAS, and hydroxycinnamoyl-CoA:shikimic acid hydroxycinnamoyltransferase/hydroxycinnamoyl-CoA:quinate hydroxycinnamoyltransferase, HST/HQT | Coleus scutellarioides |
metabolism | quinate is used as acceptor molecule by a HQT and 4-coumaroylquinate is formed, which is hydroxylated by a member of the CYP98A family to chlorogenic acid | Coleus scutellarioides |