Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Trypanosoma brucei |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CP-014553 | - |
Leishmania major | |
CP-014553 | IC50: 460 nM | Trypanosoma brucei | |
CP-030890-27 | - |
Leishmania major | |
CP-030890-27 | IC50: 250 nM | Trypanosoma brucei |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00137 | - |
myristoyl-CoA | - |
Leishmania major | |
0.00178 | - |
myristoyl-CoA | - |
Trypanosoma brucei | |
0.0113 | - |
GCGGSKVK | - |
Trypanosoma brucei | |
0.11 | - |
GQLFTSLN | - |
Leishmania major |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50500 | - |
x * 50500, SDS-PAGE | Trypanosoma brucei |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Leishmania major | Q9GPZ4 | - |
- |
Trypanosoma brucei | Q388H8 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Trypanosoma brucei |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
myristoyl-CoA + GCGGSKVK | - |
Trypanosoma brucei | N-myristoylglycyl-CGGSKVK + CoA | - |
? | |
myristoyl-CoA + GQLFTSLN | - |
Leishmania major | N-myristoylglycyl-GQLFTSLN + CoA | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 50500, SDS-PAGE | Trypanosoma brucei |
Synonyms | Comment | Organism |
---|---|---|
LmNMT | - |
Leishmania major |
myristoyl-CoA:protein N-myristoyltransferase | - |
Leishmania major |
myristoyl-CoA:protein N-myristoyltransferase | - |
Trypanosoma brucei |
TbNMT | - |
Trypanosoma brucei |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
18.2 | - |
GCGGSKVK | - |
Trypanosoma brucei | |
23.6 | - |
myristoyl-CoA | - |
Leishmania major | |
24 | - |
GQLFTSLN | - |
Leishmania major | |
76.8 | - |
myristoyl-CoA | - |
Trypanosoma brucei |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00025 | - |
IC50: 250 nM | Trypanosoma brucei | CP-030890-27 | |
0.00046 | - |
IC50: 460 nM | Trypanosoma brucei | CP-014553 |